HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromo-1-(2,5-dimethylfuran-3-yl)ethan-1-one → Ethyl 3-[4-(2,5-dimethyl-3-furyl)-2-thiazolyl]benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromo-1-(2,5-dimethylfuran-3-yl)ethan-1-one | HCID 18613869 | — |
| Reactant | Ethyl 3-thiocarbamoylbenzoate | HCID 18613909 | — |
| Product | Ethyl 3-[4-(2,5-dimethyl-3-furyl)-2-thiazolyl]benzoate | HCID 18613843 | 16% |
Reaction Steps
In the same manner as in Example 28, ethyl 3-thiocarbamoylbenzoate was reacted with 3-bromoacetyl-2,5-dimethylfuran to obtain ethyl 3-[4-(2,5-dimethyl-3-furyl)-2-thiazolyl]benzoate. The product was recrystallized from ethanol. Yield: 16%, Pale yellow prisms. Melting point: 100 to 101° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06545009B1 |
| Source dataset | uspto-grants-2003_04 |
| ORD ID | ord-ca2c2e0b69764cf1a893985e6a701e20 |
| Source note | uspto-grants-2003_04 |