Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl 4-carbamothioylbenzoate → Methyl 4-[4-(2,5-dimethyl-3-furyl)-2-thiazolyl]benzoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl 4-carbamothioylbenzoate | HCID 11401319 | — |
| 반응물 | 2-Bromo-1-(2,5-dimethylfuran-3-yl)ethan-1-one | HCID 18613869 | — |
| 생성물 | Methyl 4-[4-(2,5-dimethyl-3-furyl)-2-thiazolyl]benzoate | HCID 18613829 | 36% |
반응 단계
In the same manner as in Example 74, methyl 4-thiocarbamoylbenzoate was reacted with 3-bromoacetyl-2,5-dimethylfuran to obtain methyl 4-[4-(2,5-dimethyl-3-furyl)-2-thiazolyl]benzoate. The product was recrystallized from ethanol. Yield: 36%. Pale yellow prisms. Melting point: 103 to 105° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06545009B1 |
| 출처 데이터셋 | uspto-grants-2003_04 |
| ORD ID | ord-1de763cc337a4c25ab7b0b079e2cc011 |
| 출처 메모 | uspto-grants-2003_04 |