HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromo-1-(4-tert-butylphenyl)ethan-1-one → Methyl 4-[4-(4-t-butylphenyl)-2-thiazolyl]benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromo-1-(4-tert-butylphenyl)ethan-1-one | HCID 2324770 | — |
| Reactant | Methyl 4-carbamothioylbenzoate | HCID 11401319 | — |
| Product | Methyl 4-[4-(4-t-butylphenyl)-2-thiazolyl]benzoate | HCID 18613899 | 68% |
Reaction Steps
In the same manner as in Example 74, methyl 4-thiocarbamoylbenzoate was reacted with 4-t-butylphenacyl bromide to obtain methyl 4-[4-(4-t-butylphenyl)-2-thiazolyl]benzoate. The product was recrystallized from ethanol. Yield: 68%. Pale yellow prisms. Melting point: 154 to 155° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06545009B1 |
| Source dataset | uspto-grants-2003_04 |
| ORD ID | ord-638df5004e54440e84b29432bc584bc1 |
| Source note | uspto-grants-2003_04 |