Triethylamine → HCID 69688430, compound

HRID 1265515Notes

Reaction equation

HRID 1265515 reaction equation
[C:1]([O:5][C:6](=[O:19])[NH:7][C:8]1[CH:13]=[C:12](Cl)[C:11]([Cl:15])=[CH:10][C:9]=1[N+:16]([O-:18])=[O:17])([CH3:4])([CH3:3])[CH3:2].[NH:20]1[CH2:23][CH2:22][CH2:21]1.CCN(CC)CC>CS(C)=O>[C:1]([O:5][C:6](=[O:19])[NH:7][C:8]1[CH:13]=[C:12]([N:20]2[CH2:23][CH2:22][CH2:21]2)[C:11]([Cl:15])=[CH:10][C:9]=1[N+:16]([O-:18])=[O:17])([CH3:4])([CH3:3])[CH3:2]

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 10422AzetidineHCID 69489445HCID 69489445, compound

Product 1

HCID 69688430HCID 69688430, compound

Reagents, catalysts & solvents 1

HCID 679Dimethyl SulfoxideSolvent

Procedure

The title compound was prepared from (4,5-dichloro-2-nitro-phenyl)-carbamic acid tert.-butyl ester (Example B2) (6.14 g, 20 mmol), azetidine (2.33 mL, 34 mmol) and Et3N (8.4 mL, 60 mmol) in DMSO (40 mL) at 23° C. according to the general procedure C. Obtained as an orange solid (5.85 g).

Sources & evidence

ORD record
ord-943d1ed5c942436a9b46275774b28699
Source dataset
uspto-grants-2003_04
Patent number
US06544985B2

Reaction notes

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