Stannous chloride dihydrate → HCID 69687617, compound

HRID 1265560Notes

Reaction equation

HRID 1265560 reaction equation
[C:1]([O:5][C:6](=[O:27])[NH:7][C:8]1[CH:13]=[C:12]([N:14]([CH2:16][CH:17]2[CH2:19][CH2:18]2)[CH3:15])[C:11]([C:20]([F:23])([F:22])[F:21])=[CH:10][C:9]=1[N+:24]([O-])=O)([CH3:4])([CH3:3])[CH3:2].O.O.Cl[Sn]Cl>>[C:1]([O:5][C:6](=[O:27])[NH:7][C:8]1[CH:13]=[C:12]([N:14]([CH2:16][CH:17]2[CH2:19][CH2:18]2)[CH3:15])[C:11]([C:20]([F:23])([F:22])[F:21])=[CH:10][C:9]=1[NH2:24])([CH3:4])([CH3:2])[CH3:3]

Participants

3

Reactant 2

HCID 61436Stannous chloride dihydrateHCID 69687558[5-(Cyclopropylmethyl-methyl-amino)-2-nitro-4-trifluoromethyl-phenyl]-carbamic acid tert.-butyl ester

Product 1

HCID 69687617HCID 69687617, compound

Procedure

The title compound was prepared from [5-(cyclopropylmethyl-methyl-amino)-2-nitro-4-trifluoromethyl-phenyl]-carbamic acid tert.-butyl ester (Example C16) (5.66 g, 14.5 mmol) by reduction with SnCl2.2H2O according to the general procedure J (method b). Obtained as yellow solid (4.7 g).

Sources & evidence

ORD record
ord-0e66b4cf8c1f48b6aa5a03a61d63eeca
Source dataset
uspto-grants-2003_04
Patent number
US06544985B2

Reaction notes

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