HCID 69688409, compound → Carbamic acid,[2-amino-5-(ethylmethylamino)-4-methylphenyl]-,1,1-dimethylethyl ester

HRID 1265567Notes

Reaction equation

HRID 1265567 reaction equation
[C:1]([O:5][C:6](=[O:22])[NH:7][C:8]1[CH:13]=[C:12]([N:14]([CH2:16][CH3:17])[CH3:15])[C:11]([CH3:18])=[CH:10][C:9]=1[N+:19]([O-])=O)([CH3:4])([CH3:3])[CH3:2]>[Pd]>[C:1]([O:5][C:6](=[O:22])[NH:7][C:8]1[CH:13]=[C:12]([N:14]([CH2:16][CH3:17])[CH3:15])[C:11]([CH3:18])=[CH:10][C:9]=1[NH2:19])([CH3:2])([CH3:3])[CH3:4]

Participants

3

Reactant 1

HCID 69688409HCID 69688409, compound

Product 1

HCID 69688364Carbamic acid,[2-amino-5-(ethylmethylamino)-4-methylphenyl]-,1,1-dimethylethyl ester

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

The title compound was prepared from [5-(ethyl-methyl-amino)-4-methyl-2-nitro-phenyl]-carbamic acid tert-butyl ester (Example C22) (3.28 g, 10.6 mmol) by hydrogenation with 10% Pd/C according to the general procedure J (method a). Obtained as a purple solid (2.94 g, 99%).

Sources & evidence

ORD record
ord-c540f50ef1904be7b3d8cdf5d49f2116
Source dataset
uspto-grants-2003_04
Patent number
US06544985B2

Reaction notes

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