Stannous chloride dihydrate → HCID 69688187, compound

HRID 1265570Notes

Reaction equation

HRID 1265570 reaction equation
[C:1]([O:5][C:6](=[O:24])[NH:7][C:8]1[CH:13]=[C:12]([N:14]2[CH2:18][CH2:17][CH2:16][CH2:15]2)[C:11]([C:19]#[N:20])=[CH:10][C:9]=1[N+:21]([O-])=O)([CH3:4])([CH3:3])[CH3:2].O.O.Cl[Sn]Cl>>[C:1]([O:5][C:6](=[O:24])[NH:7][C:8]1[CH:13]=[C:12]([N:14]2[CH2:18][CH2:17][CH2:16][CH2:15]2)[C:11]([C:19]#[N:20])=[CH:10][C:9]=1[NH2:21])([CH3:4])([CH3:2])[CH3:3]

Participants

3

Reactant 2

HCID 61436Stannous chloride dihydrateHCID 69688474HCID 69688474, compound

Product 1

HCID 69688187HCID 69688187, compound

Procedure

The title compound was prepared from (4-cyano-2-nitro-5-pyrrolidin-1-yl-phenyl)-carbamic acid tert-butyl ester (Example C25) (1.82 g, 5.48 mmol) by reduction with SnCl2.2H2O according to the general procedure J (method b). Obtained as a pale brown solid (1.27 g, 77%).

Sources & evidence

ORD record
ord-dfffad0d288640de872a811d4e99790c
Source dataset
uspto-grants-2003_04
Patent number
US06544985B2

Reaction notes

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