Trifluoroacetic anhydride → HCID 18548744, compound

HRID 1265641Notes

Reaction equation

HRID 1265641 reaction equation
[C:1]([O:5][C:6](=[O:21])[CH2:7][C:8](=[O:20])[C:9]1[CH:14]=[CH:13][CH:12]=[C:11]([N:15]2[CH:19]=[CH:18][N:17]=[N:16]2)[CH:10]=1)(C)([CH3:3])[CH3:2].C(OC(C(F)(F)F)=O)(C(F)(F)F)=O>C(O)(C(F)(F)F)=O.CC(C)=O>[CH3:2][C:1]1([CH3:3])[O:5][C:6](=[O:21])[CH:7]=[C:8]([C:9]2[CH:14]=[CH:13][CH:12]=[C:11]([N:15]3[CH:19]=[CH:18][N:17]=[N:16]3)[CH:10]=2)[O:20]1

Participants

4

Reactant 2

HCID 9845Trifluoroacetic anhydrideHCID 696875993-Oxo-3-(3-[1,2,3]triazol-1-yl-phenyl)-propionic acid tert-butyl ester

Product 1

HCID 18548744HCID 18548744, compound

Reagents, catalysts & solvents 1

HCID 86586799TFA acetoneSolvent

Procedure

The title compound was prepared from 3-oxo-3-(3-[1,2,3]triazol-1-yl -phenyl)-propionic acid tert.-butyl ester (Example K23) by stirring in TFA/acetone with TFAA according to general procedure L (method b). Obtained as a beige solid (7.80 g).

Sources & evidence

ORD record
ord-4e803164c44e4e25b22c17502a4246e0
Source dataset
uspto-grants-2003_04
Patent number
US06544985B2

Reaction notes

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