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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1265664Generated: October 29, 2026

3-[3-(3-Methyl-isoxazol-5-yl)-phenyl)-3-oxo-propionic acid tert-butyl ester → HCID 86586819, compound

https://huagongshe.com/reaction/1265664

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-[3-(3-Methyl-isoxazol-5-yl)-phenyl)-3-oxo-propionic acid tert-butyl esterHCID 69592871—
ReactantHCID 69688642HCID 69688642—
ProductHCID 86586819HCID 86586819—

Reaction Steps

The title compound was prepared from [5-amino-2′-fluoro-2-(2,2,2-trifluoro-ethoxy)-biphenyl-4-yl]-carbamic acid tert.-butyl ester (Example J5) (200 mg, 0.5 mmol) and 3-[3-(3-methyl-isoxazol-5-yl)-phenyl]-3-oxo-propionic acid tert.-butyl ester (Example K4) (160 mg, 0.53 mmol) according to the general procedure M. Obtained as a white solid (40 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06544985B2
Source datasetuspto-grants-2003_04
ORD IDord-469c797593904a438ffaaa47291457ac
Source noteuspto-grants-2003_04