HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Oxo-3-(3-pyrazol-1-yl-phenyl)-propionic acid tert-butyl ester → {4-Chloro-5-dimethylamino-2-[3-oxo-3-(3-pyrazol-1-yl-phenyl)-propionylamino]-phenyl}-carbamic acid tert.-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Oxo-3-(3-pyrazol-1-yl-phenyl)-propionic acid tert-butyl ester | HCID 69687557 | — |
| Reactant | (2-Amino-4-chloro-5-dimethylamino-phenyl)-carbamic acid tert.-butyl ester | HCID 69688689 | — |
| Product | {4-Chloro-5-dimethylamino-2-[3-oxo-3-(3-pyrazol-1-yl-phenyl)-propionylamino]-phenyl}-carbamic acid tert.-butyl ester | HCID 86586838 | — |
Reaction Steps
The title compound was prepared from (2-amino-4-chloro-5-dimethylamino-phenyl)-carbamic acid tert.-butyl ester (Example J1) and 3-oxo-3-(3-pyrazol-1-yl-phenyl)-propionic acid tert.-butyl ester (Example K16) according to the general procedure M. Obtained as a light yellow solid (135 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06544985B2 |
| Source dataset | uspto-grants-2003_04 |
| ORD ID | ord-72067df22c6d4e958fbf9797e0fdbc0e |
| Source note | uspto-grants-2003_04 |