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HRID1265803

反应详情

EQUATION

反应方程式

HRID 1265803 的结构方程式

REACTANTS

反应物

2
结构：O=C(O)C(F)(F)F
HCID6422

未命名化合物

结构：CC(C)(C)OC(=O)Nc1cc(N2CCCC2)c(C(F)(F)F)cc1NC(=O)CC(=O)c1cccc(-c2cc(COC3CCCCO3)on2)c1
HCID86586843

未命名化合物

PRODUCTS

生成物

1
结构：O=C1CC(c2cccc(-c3cc(CO)on3)c2)=Nc2cc(N3CCCC3)c(C(F)(F)F)cc2N1
HCID18613525

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：ClCCl
溶剂HCID6344

Dichloromethane

CH2Cl2

PROCEDURE

实验过程

The title compound was prepared from (RS)-[2-(3-oxo-3-{3-[5-(tetrahydro-pyran-2-yloxymethyl)-isoxazol-3-yl]-phenyl}-propionylamino)-5-pyrrolidin-1-yl-4-trifluoromethyl-phenyl]-carbamic acid tert.-butyl ester (Example M51) by treatment with TFA in CH2Cl2 according to the general procedure N. Obtained as a yellow solid (224 mg).