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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1265813Generated: October 28, 2026

Trifluoroacetic acid → HCID 18613510, compound

https://huagongshe.com/reaction/1265813

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 86586853HCID 86586853—
SolventDichloromethaneHCID 6344—
ProductHCID 18613510HCID 18613510—

Reaction Steps

The title compound was prepared from (RS)-[5-dimethylamino-2-(3-oxo-3-{3-[4-(tetrahydro-pyran-2-yloxymethyl)-isoxazol-3-yl]-phenyl}-propionylamino)-4-trifluoromethyl-phenyl]-carbamic acid tert.-butyl ester (Example M61) by treatment with TFA in CH2Cl2 according to the general procedure N. Obtained as a light yellow solid (50 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06544985B2
Source datasetuspto-grants-2003_04
ORD IDord-63e7f90a161044e3b7077b70fed961be
Source noteuspto-grants-2003_04