HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 18613196, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 86586855 | HCID 86586855 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 18613196 | HCID 18613196 | — |
Reaction Steps
The title compound was prepared from (RS)-[5-dimethylamino-2-(3-{3-[2-methyl-4-(tetrahydro-pyran-2-yloxymethyl)-2H-pyrazol-3-yl]-phenyl}-3-oxo-propionyl-amino)-4-trifluoromethyl-phenyl]-carbamic acid tert.-butyl ester (Example M63) by treatment with TFA in CH2Cl2 according to the general procedure N. Obtained as a yellow solid (272 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06544985B2 |
| Source dataset | uspto-grants-2003_04 |
| ORD ID | ord-f80759d8681144acb55fad0d34b7f6f6 |
| Source note | uspto-grants-2003_04 |