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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1265833Generated: October 30, 2026

Trifluoroacetic acid → HCID 18613320, compound

https://huagongshe.com/reaction/1265833

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 86586864HCID 86586864—
SolventDichloromethaneHCID 6344—
ProductHCID 18613320HCID 18613320—

Reaction Steps

The title compound was prepared from (RS)-[5-dimethylamino-4-methyl-2-(3oxo-3-{3-[5-(tetrahydro-pyran-2-yloxymethyl)-[1,2,3]triazol-1-yl]-phenyl}-propionyl-amino)-phenyl]-carbamic acid tert-butyl ester (Example M77) (0.42 g, 0.71 mmol) by treatment with TFA in CH2Cl2 according to the general procedure N. Obtained as a pale yellow solid (200 mg, 72%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06544985B2
Source datasetuspto-grants-2003_04
ORD IDord-285fe90b65b54176bf83b497eb5471b6
Source noteuspto-grants-2003_04