HRID1265849

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6422

未命名化合物

反应SMILES：CC(C)N(C)c1cc(NC(=O)OC(C)(C)C)c(NC(=O)CC(=O)c2cccc(-n3nncc3COC3CCCCO3)c2)cc1C#N

HCID86586879

未命名化合物

PRODUCTS

产物

反应SMILES：CC(C)N(C)c1cc2c(cc1C#N)NC(=O)CC(c1cccc(-n3nncc3CO)c1)=N2

HCID69688302

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6344

Dichloromethane

CH2Cl2

PROCEDURE

实验过程

The title compound was prepared from (RS)-[4-cyano-5-(isopropyl-methyl-amino)-2-(3-oxo-3-{3-[5-(tetrahydro-pyran-2-yloxymethyl)-[1,2,3]triazol-1-yl]-phenyl}-propionylamino)-phenyl]-carbamic acid tert-butyl ester (Example M96) (0.45 g, 0.71 mmol) by treatment with TFA in CH2Cl2 according to the general procedure N. Obtained as a yellow solid (236 mg, 77%).