HCID 69701971, compound → HCID 69701319, compound

HRID 1266014Notes

Reaction equation

HRID 1266014 reaction equation
[C:1]1(=[O:14])[N:12]2[C:13]3[C:5](=[CH:6][CH2:7][CH2:8][C:9]=3[CH:10]=[CH:11]2)[CH2:4][NH:3][CH2:2]1>O>[C:1]1(=[O:14])[N:12]2[C:13]3[C:9]([CH:10]=[CH:11]2)=[CH:8][CH:7]=[CH:6][C:5]=3[CH2:4][NH:3][CH2:2]1

Participants

3

Reactant 1

HCID 69701971HCID 69701971, compound

Product 1

HCID 69701319HCID 69701319, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

This known compound was prepared from 3,4,6,7-tetrahydro-2H-[1,4]diazepino[6,7,1-hi]indol-1-one (Example 41) according to the general procedure of Hester et al. and references cited therein (Hester et al., J. Med. Chem. 13, 827 (1970)): 1H NMR (DMSO-d6) δ 3.52-3.56 (m, 2H), 4.31-4.36 (m, 2H), 6.53 (d, 1H, J=3.0 Hz), 7.11 (t, 1H, J=6.0 Hz), 7.38 (d, 1H, J=3.0 Hz), 7.70 (d, 1H, J=6.0 Hz), 7.80 (d, 1H, J=6.0 Hz), 8.30 (bs, 1H). LRMS (M+) 186. Anal. (C11H10N2O.0.05 H2O) C, H, N.

Sources & evidence

ORD record
ord-72d1dc80b7a045338fecabd2cebfc6af
Source dataset
uspto-grants-2003_04
Patent number
US06548494B1

Reaction notes

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