Pyrrolidine → HCID 70009270, compound

HRID 1266051Notes

Reaction equation

HRID 1266051 reaction equation
Cl[CH:2]([C:10]1[CH:15]=[CH:14][C:13]([C:16]2[N:21]3[CH2:22][CH2:23][C:24]4[NH:25][C:26](=[O:29])[CH:27]=[CH:28][C:19]([C:20]=43)=[CH:18][N:17]=2)=[CH:12][CH:11]=1)[CH2:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.[NH:30]1[CH2:34][CH2:33][CH2:32][CH2:31]1>C(Cl)(Cl)Cl>[C:4]1([CH2:3][CH:2]([C:10]2[CH:15]=[CH:14][C:13]([C:16]3[N:21]4[CH2:22][CH2:23][C:24]5[NH:25][C:26](=[O:29])[CH:27]=[CH:28][C:19]([C:20]=54)=[CH:18][N:17]=3)=[CH:12][CH:11]=2)[N:30]2[CH2:34][CH2:33][CH2:32][CH2:31]2)[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1

Participants

4

Reactant 2

HCID 31268PyrrolidineHCID 69701519HCID 69701519, compound

Product 1

HCID 70009270HCID 70009270, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

This compound was prepared from intermediate 247b and pyrrolidine according to the procedure described in Example 245, with the exception of chloroform as solvent. Received 40 mg (11%).

Sources & evidence

ORD record
ord-335f30528bd9402d849f8402e080c7ce
Source dataset
uspto-grants-2003_04
Patent number
US06548494B1

Reaction notes

Loading…