2,2-Diphenylacetyl chloride → N-(4-Methoxy-butyl)-2,2-diphenyl-acetamide

HRID 1266233Notes

Reaction equation

HRID 1266233 reaction equation
[C:1]1([CH:7]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[C:8](Cl)=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:17][O:18][CH2:19][CH2:20][CH2:21][CH2:22][NH2:23]>>[CH3:17][O:18][CH2:19][CH2:20][CH2:21][CH2:22][NH:23][C:8](=[O:9])[CH:7]([C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)[C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 746372,2-Diphenylacetyl chlorideHCID 5339094-Methoxybutan-1-amine

Product 1

HCID 18549697N-(4-Methoxy-butyl)-2,2-diphenyl-acetamide

Procedure

The title compound, white solid, m.p. 75.5-76.8° C. and MS: m/e=298 (M+H+) was prepared in accordance with the general method of example 1 from diphenylacetyl chloride and 4-methoxy-butylamine.

Sources & evidence

ORD record
ord-46632b810a9748c4a21f6494de8dfc90
Source dataset
uspto-grants-2003_04
Patent number
US06548522B1

Reaction notes

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