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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1266487Generated: October 31, 2026

2,4-Difluorobenzaldehyde → E-2,4-difluorostyryl 4-fluorobenzyl sulfone

https://huagongshe.com/reaction/1266487

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-DifluorobenzaldehydeHCID 73770—
Reactant[(4-Fluorobenzyl)sulfonyl]acetic acidHCID 11447598—
ProductE-2,4-difluorostyryl 4-fluorobenzyl sulfoneHCID 988323268%

Reaction Steps

A solution of 4-fluorobenzyl sulfonylacetic acid (0.01 mol) and 2,4difluorobenzaldehyde (0.01 mol) was subjected to Procedure 1. The title compound was obtained in 68% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06548553B2
Source datasetuspto-grants-2003_04
ORD IDord-0dbaf2480bbe4108a5e8868157cf920f
Source noteuspto-grants-2003_04