Ethyl α-(acetylamino)-6-quinolinepropanoate → HCID 21925070, compound

HRID 1266551Notes

Reaction equation

HRID 1266551 reaction equation
C([O:3][C:4](=[O:21])[CH:5]([CH2:10][C:11]1[CH:12]=[C:13]2[C:18](=[CH:19][CH:20]=1)[N:17]=[CH:16][CH:15]=[CH:14]2)[NH:6]C(=O)C)C>Cl>[N:17]1[C:18]2[C:13](=[CH:12][C:11]([CH2:10][CH:5]([C:4]([OH:21])=[O:3])[NH2:6])=[CH:20][CH:19]=2)[CH:14]=[CH:15][CH:16]=1

Participants

3

Reactant 1

HCID 21925091Ethyl α-(acetylamino)-6-quinolinepropanoate

Product 1

HCID 21925070HCID 21925070, compound

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

N-Acetyl β-(6-quinolinyl)-D,L-alanine ethyl ester (728 mg, 2.55 mmol) was heated at reflux in 6N HCl (20 mL). After 20 h, the reaction mixture was concentrated to dryness and the residue was dried in vacuo to provide the title compound, which was used directly in the next reaction.

Workup

  1. concentrationthe reaction mixture was concentrated to dryness
  2. customthe residue was dried in vacuo

Sources & evidence

ORD record
ord-ee145dfe995742d48ae7a695c6c27dda
Source dataset
uspto-grants-2003_04
Patent number
US06548668B2

Reaction notes

Loading…