Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 11065016 | HCID 11065016 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 18551811 | HCID 18551811 | — |
Reaction Steps
0.2 ml of concentrated hydrochloric acid is added to 3.0 g of 2-benzylsulfanyl-5-hydroxymethyl-4,5-dihydrothiazol-4-ol in 25 ml of ethanol. The mixture is stirred at 50° C. for 12 hours, the solvent is removed in vacuo, and the residue is chromatographed on silica gel (ether:hexane; 1:1). The title compound is obtained in the form of a yellow oil (compound 3.1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06548676B1 |
|---|
| Source dataset | uspto-grants-2003_04 |
|---|
| ORD ID | ord-c5ff8bb421c248809d0c3333e6399d37 |
|---|
| Source note | uspto-grants-2003_04 |
|---|
