HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → 5-Ethoxy-2-nitro-4-(trifluoromethyl)aniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | 5-Chloro-2-nitro-4-(trifluoromethyl)aniline | HCID 2773813 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | 5-Ethoxy-2-nitro-4-(trifluoromethyl)aniline | HCID 22317155 | — |
Reaction Steps
The title compound was prepared from 5-chloro-2-nitro-4-trifluoromethyl-phenylamine [CAS-No. 35375-74-7] (7.06 g, 29.3 mmol) and KOH (4.26 g, 64.6 mmol) in EtOH (30 mL) and DMSO (60 mL) according to the general procedure E. Obtained as a yellow solid (4.20 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06548495B2 |
| Source dataset | uspto-grants-2003_04 |
| ORD ID | ord-aa8939a91acb4b2c8a9623b5dc783888 |
| Source note | uspto-grants-2003_04 |