HuagongsheHuagongshe Chemistry Print Report · For research reference only
Stannous chloride dihydrate → (2-Amino-4-cyano-5-morpholin-4-yl-phenyl)-carbamic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Stannous chloride dihydrate | HCID 61436 | — |
| Reactant | (4-Cyano-5-morpholin-4-yl-2-nitro-phenyl)-carbamic acid tert-butyl ester | HCID 69780848 | — |
| Product | (2-Amino-4-cyano-5-morpholin-4-yl-phenyl)-carbamic acid tert-butyl ester | HCID 69779753 | — |
Reaction Steps
The title compound was prepared from (4-cyano-5-morpholin-4-yl-2-nitro-phenyl)-carbamic acid tert-butyl ester (Example B3) (5.01 g, 14.4 mmol) by reduction with SnCl2.2H2O according to the general procedure J (method b). Obtained as a pink solid (4.18 g, 91%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06548495B2 |
| Source dataset | uspto-grants-2003_04 |
| ORD ID | ord-e0ae79dcdd4c47e8930c6df21315dfad |
| Source note | uspto-grants-2003_04 |