HuagongsheHuagongshe Chemistry Print Report · For research reference only
Stannous chloride dihydrate → (2-Amino-5-chloro-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Stannous chloride dihydrate | HCID 61436 | — |
| Reactant | (5-Chloro-2-nitro-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester | HCID 69489376 | — |
| Product | (2-Amino-5-chloro-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester | HCID 69489727 | — |
Reaction Steps
The title compound was prepared from (5-chloro-2-nitro-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester (Example A11) (7.00 g, 20.5 mmol) by reduction with SnCl2.2H2O according to the general procedure J (method b). Obtained as a yellow solid (3.13 g, 49%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06548495B2 |
| Source dataset | uspto-grants-2003_04 |
| ORD ID | ord-2728bbb274964a0589eda19b39c089f1 |
| Source note | uspto-grants-2003_04 |