HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(2,2-Dimethyl-6-oxo-6H-[1,3]dioxin-4-yl)-benzonitrile → 3-(3-Cyano-phenyl)-N-[5-(3-hydroxymethyl-pyrrol-1-yl)-2-nitro-phenyl]-3-oxo-propionamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(2,2-Dimethyl-6-oxo-6H-[1,3]dioxin-4-yl)-benzonitrile | HCID 11736337 | — |
| Reactant | [1-(3-Amino-4-nitro-phenyl)-1H-pyrrol-3-yl]-methanol | HCID 18548757 | — |
| Product | 3-(3-Cyano-phenyl)-N-[5-(3-hydroxymethyl-pyrrol-1-yl)-2-nitro-phenyl]-3-oxo-propionamide | HCID 18548865 | — |
Reaction Steps
The title compound was prepared from [1-(3-amino-4-nitro-phenyl)-1H-pyrrol-3-yl]-methanol (Example F5) and 3-(2,2-dimethyl-6-oxo-6H-[1,3]dioxin-4-yl)-benzonitrile (Example L1) according to the general procedure M. Obtained as an orange solid (77 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06548495B2 |
| Source dataset | uspto-grants-2003_04 |
| ORD ID | ord-f3834d1b4b374191a84e9ffaf70e8e0e |
| Source note | uspto-grants-2003_04 |