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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1266792Generated: October 31, 2026

3-(2,2-Dimethyl-6-oxo-6H-[1,3]dioxin-4-yl)-benzonitrile → 3-(3-Cyano-phenyl)-N-[2-nitro-5-(3-phenyl-pyrrol-1-yl)-phenyl]-3-oxo-propionamide

https://huagongshe.com/reaction/1266792

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(2,2-Dimethyl-6-oxo-6H-[1,3]dioxin-4-yl)-benzonitrileHCID 11736337—
Reactant2-Nitro-5-(3-phenyl-pyrrol-1-yl)-phenylamineHCID 18548849—
Product3-(3-Cyano-phenyl)-N-[2-nitro-5-(3-phenyl-pyrrol-1-yl)-phenyl]-3-oxo-propionamideHCID 18548769—

Reaction Steps

The title compound was prepared from 2-nitro-5-(3-phenyl-pyrrol-1-yl)-phenylamine (Example F6) and 3-(2,2-dimethyl-6-oxo-6H-[1,3]dioxin-4-yl)-benzonitrile (Example L1) according to the general procedure M. Obtained as an orange solid (267 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06548495B2
Source datasetuspto-grants-2003_04
ORD IDord-1a757c6edabe4b35bd9d63cd901bfac0
Source noteuspto-grants-2003_04