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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1266800Generated: November 3, 2026

6-(3-Imidazol-1-yl-phenyl)-2,2-dimethyl-[1,3]dioxin-4-one → HCID 86586975, compound

https://huagongshe.com/reaction/1266800

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-(3-Imidazol-1-yl-phenyl)-2,2-dimethyl-[1,3]dioxin-4-oneHCID 22224895—
ReactantHCID 69781137HCID 69781137—
ProductHCID 86586975HCID 86586975—

Reaction Steps

The title compound was prepared from (2-amino-5-cyanomethyl-4-iodo-phenyl)-carbamic acid tert.-butyl ester (Example J6) (363 mg, 0.973 mmol) and 6-(3-imidazol-1-yl-phenyl)-2,2-dimethyl-[1,3]dioxin-4-one (Example L3) (411 mg, 1.52 mmol) according to the general procedure M. Obtained as a yellow oil (523 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06548495B2
Source datasetuspto-grants-2003_04
ORD IDord-f3fd74035f6447df843dc1c0cd799e3a
Source noteuspto-grants-2003_04