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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1266809Generated: October 30, 2026

HCID 12048026, compound → HCID 86586985, compound

https://huagongshe.com/reaction/1266809

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 12048026HCID 12048026—
Reactant3-Oxo-3-(3-[1,2,4]triazol-4-yl-phenyl)-propionic acid ethyl esterHCID 69592875—
ProductHCID 86586985HCID 86586985—

Reaction Steps

The title compound was prepared from (2-amino-5-morpholin-4-yl-4-trifluoromethyl-phenyl)-carbamic acid tert.-butyl ester (Example J1) (434 mg, 1.2 mmol) and 3-oxo-3-(3-[1,2,4]triazol-4-yl-phenyl)-propionic acid ethyl ester [CAS-No. 335255-97-5] (259 mg, 1.0 mmol) according to the general procedure M. Obtained as an off-white solid (372 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06548495B2
Source datasetuspto-grants-2003_04
ORD IDord-dbf369a9816b4ec8acc4eef8a1080b30
Source noteuspto-grants-2003_04