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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1266828Generated: November 4, 2026

Trifluoroacetic acid → HCID 18548755, compound

https://huagongshe.com/reaction/1266828

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 86586966HCID 86586966—
SolventDichloromethaneHCID 6344—
ProductHCID 18548755HCID 18548755—

Reaction Steps

The title compound was prepared from {2-[3-(2-cyano-pyridin-4-yl)-3-oxo-propionylamino]-5-morpholin-4-yl-4-trifluoromethyl-phenyl}-carbamic acid tert.-butyl ester (Example M2) by treatment with TFA in CH2Cl2 according to the general procedure N. Obtained as a yellow solid (11 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06548495B2
Source datasetuspto-grants-2003_04
ORD IDord-5ef7119f68c24b479b90e283dde49fa2
Source noteuspto-grants-2003_04