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HRID1266840

反应详情

EQUATION

反应方程式

HRID 1266840 的结构方程式

REACTANTS

反应物

1
结构：COC(=O)c1cccn1-c1ccc([N+](=O)[O-])c(NC(=O)CC(=O)c2cccc(C#N)c2)c1
HCID86586970

未命名化合物

PRODUCTS

生成物

1
结构：COC(=O)c1cccn1-c1ccc2c(c1)NC(=O)CC(c1cccc(C#N)c1)=N2
HCID69781031

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

2
结构：CC(=O)O.[Fe]
催化剂HCID45051903

未命名化合物

结构：C1CCOC1.O
溶剂HCID21881883

Oxolane--water (1/1)

C4H10O2

PROCEDURE

实验过程

The title compound was prepared from 1-{3-[3-(3-cyano-phenyl)-3-oxo-propionylamino]-4-nitro-phenyl}-1H-pyrrole-2-carboxylic acid methyl ester (Example M15) by reductive cyclization with Fe/HOAc in THF/H2O at 80° C. according to the general procedure J (method d). Obtained as a brown solid (323 mg).