HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 18548814, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 18548749 | HCID 18548749 | — |
| Reactant | (2-Amino-4-pyrrol-1-yl-phenyl)-carbamic acid tert-butyl ester | HCID 69488996 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 18548814 | HCID 18548814 | — |
Reaction Steps
The title compound was prepared from (2-amino-4-pyrrol-1-yl-phenyl)-carbamic acid tert.-butyl ester (Example J2) (137 mg) and 2,2-dimethyl-6-(3-oxazol-2-yl-phenyl)-[1,3]dioxin-4-one (Example L5) (271 mg) according to the general procedure M. The obtained material was deprotected and cyclized by treatment with TFA in CH2Cl2 according to the general procedure N. Obtained as a light yellow solid (83 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06548495B2 |
| Source dataset | uspto-grants-2003_04 |
| ORD ID | ord-b7df72da1497447e9f71d9994e28cdd4 |
| Source note | uspto-grants-2003_04 |