HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → HCID 69780802, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | 4-[3-(4-oxo-7-pyrrol-1-yl-4,5-dihydro-3H-benzo[b][1,4]diazepin-2-yl)-phenyl]-thiazole-2-carboxylic acid ethyl ester | HCID 69780571 | — |
| Product | HCID 69780802 | HCID 69780802 | — |
Reaction Steps
A sample of 4-[3-(4-oxo-7-pyrrol-1-yl-4,5-dihydro-3H-benzo[b][1,4]diazepin-2-yl)-phenyl]-thiazole-2-carboxylic acid ethyl ester (Example 28) (0.07 g) was reacted with ammonia in an analogous manner to the procedure described in Example 27 to give the title compound (0.05 g) as a light-yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06548495B2 |
| Source dataset | uspto-grants-2003_04 |
| ORD ID | ord-e1b6af9e3d074f8bbb1ddd2044c3b6f4 |
| Source note | uspto-grants-2003_04 |