HRID1266877

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6422

未命名化合物

反应SMILES：CC(C)(C)OC(=O)Nc1cc(N2CCOCC2)c(C#N)cc1NC(=O)CC(=O)c1cccc(-n2nncc2COC2CCCCO2)c1

HCID86586992

未命名化合物

PRODUCTS

产物

反应SMILES：N#Cc1cc2c(cc1N1CCOCC1)N=C(c1cccc(-n3nncc3CO)c1)CC(=O)N2

HCID18548725

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6344

Dichloromethane

CH2Cl2

PROCEDURE

实验过程

The title compound was prepared from (RS)-[4-cyano-5-morpholin-4-yl-2-(3-oxo-3-{3-[5-(tetrahydro-pyran-2-yloxymethyl)-[1,2,3]triazol-1-yl]-phenyl}-propionylamino)-phenyl]-carbamic acid tert-butyl ester (Example M41) (0.36 g, 0.56 mmol) by treatment with TFA in CH2Cl2 according to the general procedure N. Obtained as a yellow solid (152 mg, 61%).