反应详情

温度

50 °C

A reaction flask was loaded with 2-chloro-3,6-dimethylpyrazine (10 g) and ethanol (15 ml), and heated up to 50° C. with stirring. To this, a mixture of hydrazine monohydrate (11.2 g) and ethanol (10 ml) was dropwise added in one hour. The temperature was raised to the reflux temperature, followed by stirring for six hours. The heating was stopped and the reaction mixture was condensed by an evaporator. The precipitated crystals were filtrated for collection and dried to give 2-hydrazino-3,6-dimethylpyrazine (2.7 g).

1. additionwas dropwise added in one hour
2. temperatureThe temperature was raised to the reflux temperature
3. stirringby stirring for six hours
4. customcondensed
5. customby an evaporator
6. filtrationThe precipitated crystals were filtrated for collection
7. customdried