Hydrazine hydrate (1:1) → 3-Chloro-2-hydrazinyl-5-(trifluoromethyl)pyridine

참여 물질

반응 단계

A reaction flask was loaded with 2,3-dichloro-5-trifluoromethylpyridine (15 g) and ethanol (90 ml), followed by dropwise addition of hydrazine monohydrate (10.4 g) to the flask in one hour with stirring. After stirring overnight, the reaction mixture was filtrated, and the filtrate was condensed to precipitate crystals. The crystals were filtrated for collection and air-dried to give 3-chloro-2-hydrazino-5-trifluoromethylpyridine (9.1 g).

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