反应详情

A reaction flask was loaded with 2,3-dichloro-5-trifluoromethylpyridine (15 g) and ethanol (90 ml), followed by dropwise addition of hydrazine monohydrate (10.4 g) to the flask in one hour with stirring. After stirring overnight, the reaction mixture was filtrated, and the filtrate was condensed to precipitate crystals. The crystals were filtrated for collection and air-dried to give 3-chloro-2-hydrazino-5-trifluoromethylpyridine (9.1 g).

1. stirringAfter stirring overnight
2. filtrationthe reaction mixture was filtrated
3. customcondensed
4. customto precipitate crystals
5. filtrationThe crystals were filtrated for collection
6. customair-dried