ethyl (2R)-2-hydroxypropanoate → n-[(1Rs,2rs)-1,2,3,4-tetrahydro-1-hydroxy-2-naphthyl]-alanine ethyl ester

HRID 1267211Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1267211
[CH2:1]([O:3][C:4](=[O:8])[C@@H:5]([CH3:7])O)[CH3:2].[OH:9][CH:10]1[C:19]2[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=2)[CH2:13][CH2:12][CH:11]1[NH2:20]>>[CH2:1]([O:3][C:4](=[O:8])[C@H:5]([CH3:7])[NH:20][CH:11]1[CH2:12][CH2:13][C:14]2[C:19](=[CH:18][CH:17]=[CH:16][CH:15]=2)[CH:10]1[OH:9])[CH3:2]

Komponenten

3

Edukt 2

HCID 637513ethyl (2R)-2-hydroxypropanoateHCID 131101602-Amino-1,2,3,4-tetrahydronaphthalen-1-ol

Produkt 1

HCID 20578894n-[(1Rs,2rs)-1,2,3,4-tetrahydro-1-hydroxy-2-naphthyl]-alanine ethyl ester

Versuchsvorschrift

Following General Procedure AM using Ethyl-D-lactate (Fluka) and N-[(1RS,2RS)-1,2,3,4-tetrahydro-1-hydroxy-2-naphthyl]-amine (Liebigs Ann. Chem. 1992, pp273, incorporated herein by reference), the title compound was prepared. C15H21NO3 (MW=263.335); mass spectroscopy (MH+) 264.

Quellen und Nachweise

ORD-Eintrag
ord-c8be7d0503fa4a4fa02dfd5180c7c5f8
Quelldatensatz
uspto-grants-2003_04
Patentnummer
US06552013B1

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