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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1267211Generated: October 25, 2026

ethyl (2R)-2-hydroxypropanoate → n-[(1Rs,2rs)-1,2,3,4-tetrahydro-1-hydroxy-2-naphthyl]-alanine ethyl ester

https://huagongshe.com/reaction/1267211

Reaction equation

Participants

RoleNameHCIDCharge
Reactantethyl (2R)-2-hydroxypropanoateHCID 637513—
Reactant2-Amino-1,2,3,4-tetrahydronaphthalen-1-olHCID 13110160—
Productn-[(1Rs,2rs)-1,2,3,4-tetrahydro-1-hydroxy-2-naphthyl]-alanine ethyl esterHCID 20578894—

Reaction Steps

Following General Procedure AM using Ethyl-D-lactate (Fluka) and N-[(1RS,2RS)-1,2,3,4-tetrahydro-1-hydroxy-2-naphthyl]-amine (Liebigs Ann. Chem. 1992, pp273, incorporated herein by reference), the title compound was prepared. C15H21NO3 (MW=263.335); mass spectroscopy (MH+) 264.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06552013B1
Source datasetuspto-grants-2003_04
ORD IDord-c8be7d0503fa4a4fa02dfd5180c7c5f8
Source noteuspto-grants-2003_04