反应详情

Ex-31a) A suspension of ethyl acrylate, 1-nitrohexane, K2CO3, and Aliquat 336 (6 drops) is sonicated for 5 h. To the reaction is added Et2O . The reaction mixture is filtered, extracted with brine, dried over Na2SO4 (anhydrous), filtered, and concentrated under reduced pressure to give a yellow liquid. The product is purified by column chromatography to give methyl 4-nitrononanoate.

1. customis sonicated for 5 h
2. filtrationThe reaction mixture is filtered
3. extractionextracted with brine
4. dry with materialdried over Na2SO4 (anhydrous)
5. filtrationfiltered
6. concentrationconcentrated under reduced pressure
7. customto give a yellow liquid
8. customThe product is purified by column chromatography