Sodium ethoxide → HCID 23500526, compound

HRID 1267235Notes

Reaction equation

HRID 1267235 reaction equation
Br[CH2:2][CH:3]1[N:9]2[C:10](=[O:13])[O:11][N:12]=[C:8]2[CH2:7][CH2:6][CH2:5][CH2:4]1.[O-:14][CH2:15][CH3:16].[Na+]>C(O)C>[CH2:15]([O:14][CH2:2][CH:3]1[N:9]2[C:10](=[O:13])[O:11][N:12]=[C:8]2[CH2:7][CH2:6][CH2:5][CH2:4]1)[CH3:16]

Participants

4

Reactant 2

HCID 2723922Sodium ethoxideHCID 9837766HCID 9837766, compound

Product 1

HCID 23500526HCID 23500526, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Ex-37) To the product of Example 37a or the product of Example 15 in ethanol is added an ethanolic solution of sodium ethoxide. After thin layer chromatography indicates the reaction is complete, it is concentrated and the residue partitioned between water and an extraction solvent. The dried organic layer is stripped of all solvent and the residue chromatographed to produce the title material.

Workup

  1. concentrationit is concentrated
  2. customthe residue partitioned between water
  3. customthe residue chromatographed

Sources & evidence

ORD record
ord-ddc5ea88ca76427e9f1a4ed801bc41fd
Source dataset
uspto-grants-2003_04
Patent number
US06552052B2

Reaction notes

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