2,4-Difluoroaniline → HCID 14762953, compound
Reaction equation
Br[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][C:9]([OH:11])=[O:10].[F:12][C:13]1[CH:19]=[C:18]([F:20])[CH:17]=[CH:16][C:14]=1[NH2:15]>>[F:12][C:13]1[CH:19]=[C:18]([F:20])[CH:17]=[CH:16][C:14]=1[NH:15][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][C:9]([OH:11])=[O:10]Participants
3
Procedure
In the manner described in example 3, 2-bromophenylacetic acid was condensed with 2,4-difluoroaniline to yield 2-[(2,4-difluorophenyl)amino]phenylacetic acid.
Sources & evidence
- ORD record
- ord-110cf966b7554319815f2a021cf2a366
- Source dataset
- uspto-grants-2003_04
- Patent number
- US06552077B2
Reaction notes
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