反应详情

473.9 mg (19.5 mmols) of metal magnesium and 19.5 ml of diethyl ether were put into a 100-ml three-neck flask, to which were added a few drops of 1,2-dibromoethane. Then, 2.65 g (17.6 mmols) of neopentyl bromide was dropwise added thereto over a period of 50 minutes. This was ripened under reflux for 8 hours, and the disappearance of neopentyl bromide from it was confirmed. After restored to room temperature, the resulting solution was dropwise added to a solution of 2.60 g (15.8 mmols) of n-propyltrimethoxysilane in diethyl ether, and then refluxed for 14 hours. The disappearance of n-propyltrimethoxysilane from it was confirmed. 5 ml of methanol was added to this, and the resulting solution was filtered, dried, distilled and passed through a separation column to obtain 1.91 g of neopentyl-n-pentyldimethoxysilane. Its purity was 98.9%, and its yield was 59.5%.

1. temperatureunder reflux for 8 hours
2. customAfter restored to room temperature
3. temperaturerefluxed for 14 hours
4. filtrationwas filtered
5. customdried
6. distillationdistilled
7. custompassed through a separation column