(4-Methoxyphenyl)boronic acid → HCID 18546797, compound
Reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6](B(O)O)=[CH:5][CH:4]=1.Cl[C:13]1[CH:14]=[C:15]([CH:21]=[CH:22][N:23]=1)[C:16]([O:18][CH2:19][CH3:20])=[O:17]>>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:13]2[CH:14]=[C:15]([CH:21]=[CH:22][N:23]=2)[C:16]([O:18][CH2:19][CH3:20])=[O:17])=[CH:5][CH:4]=1Participants
3
Procedure
4-Methoxyphenylboronic acid (179 mg) and ethyl 2-chloroisonicotinate (200 mg) were treated in the same manner as in Preparation Example 1 to obtain the title compound.
Sources & evidence
- ORD record
- ord-e193706406b0477bb4d0210cb409ac47
- Source dataset
- uspto-grants-2003_04
- Patent number
- US06552188B2
Reaction notes
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