Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1267639Generated: October 30, 2026

Ethyl 5-chloronicotinate → Ethyl 5-(3,4,5-trimethoxyphenyl)nicotinate

https://huagongshe.com/reaction/1267639

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 5-chloronicotinateHCID 210009—
Reactant3,4,5-Trimethoxybenzeneboronic acidHCID 2734390—
ProductEthyl 5-(3,4,5-trimethoxyphenyl)nicotinateHCID 22557861—

Reaction Steps

3,4,5-Trimethoxyphenylboronic acid (6.36 g) and ethyl 5-chloronicotinate (6.90 g) were reacted in the same manner as in Preparation Example 1 to obtain the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06552188B2
Source datasetuspto-grants-2003_04
ORD IDord-5501bd2d582e4b7f9c86c14a7aadf539
Source noteuspto-grants-2003_04