HRID1267671

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID7021

3-(3,4,5-Trimethoxyphenyl)-2-propenoic acid

C12H14O5

结构：COc1cc(-c2cc(CN3CCNCC3)ccn2)cc(OC)c1OC

HCID12021155

未命名化合物

PRODUCTS

生成物

结构：COc1cc(C=CC(=O)N2CCN(Cc3ccnc(-c4cc(OC)c(OC)c(OC)c4)c3)CC2)cc(OC)c1OC

HCID69183042

未命名化合物

PROCEDURE

实验过程

1-[[2-(3,4,5-Trimethoxyphenyl)pyridin-4-yl]methyl]-piperazine (103 mg) and 3,4,5-trimethoxycinnamic acid (65 mg) were reacted in the same manner as in Example 56 to obtain the title compound as a free base.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-ed81225b5b9c41218ed7e369410c4c1e
来源数据集: uspto-grants-2003_04
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06552188B2
来源说明: uspto-grants-2003_04

反应 SMILES

[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:13]2[CH:18]=[C:17]([CH2:19][N:20]3[CH2:25][CH2:24][NH:23][CH2:22][CH2:21]3)[CH:16]=[CH:15][N:14]=2)[CH:6]=[C:7]([O:11][CH3:12])[C:8]=1[O:9][CH3:10].[CH3:26][O:27][C:28]1[CH:29]=[C:30]([CH:36]=[C:37]([O:41][CH3:42])[C:38]=1[O:39][CH3:40])[CH:31]=[CH:32][C:33](O)=[O:34]>>[CH3:42][O:41][C:37]1[CH:36]=[C:30]([CH:29]=[C:28]([O:27][CH3:26])[C:38]=1[O:39][CH3:40])[CH:31]=[CH:32][C:33]([N:23]1[CH2:24][CH2:25][N:20]([CH2:19][C:17]2[CH:16]=[CH:15][N:14]=[C:13]([C:5]3[CH:6]=[C:7]([O:11][CH3:12])[C:8]([O:9][CH3:10])=[C:3]([O:2][CH3:1])[CH:4]=3)[CH:18]=2)[CH2:21][CH2:22]1)=[O:34]