HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(3,4,5-Trimethoxyphenyl)acrylic acid → N-(3,4,5-trimethoxycinnamoyl)-N'-[[2-(3,4,5-trimethoxyphenyl)pyridin-4-yl]methyl]piperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(3,4,5-Trimethoxyphenyl)acrylic acid | HCID 7021 | — |
| Reactant | 1-[[2-(3,4,5-Trimethoxyphenyl)pyridin-4-yl]-methyl]piperazine | HCID 12021155 | — |
| Product | N-(3,4,5-trimethoxycinnamoyl)-N'-[[2-(3,4,5-trimethoxyphenyl)pyridin-4-yl]methyl]piperazine | HCID 69183042 | — |
Reaction Steps
1-[[2-(3,4,5-Trimethoxyphenyl)pyridin-4-yl]methyl]-piperazine (103 mg) and 3,4,5-trimethoxycinnamic acid (65 mg) were reacted in the same manner as in Example 56 to obtain the title compound as a free base.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06552188B2 |
| Source dataset | uspto-grants-2003_04 |
| ORD ID | ord-ed81225b5b9c41218ed7e369410c4c1e |
| Source note | uspto-grants-2003_04 |