HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl bromopyruvate → 1-Carbethoxycarbonylmethyl-2-amino-3-carbamoyl-quinoxalinium bromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl bromopyruvate | HCID 66144 | — |
| Reactant | 3-Aminoquinoxaline-2-carboxamide | HCID 816972 | — |
| Reactant | Ethyl 3-Chloroquinoxaline-2-carboxylate | HCID 12283436 | — |
| Solvent | 1,2-Dimethoxyethane | HCID 8071 | — |
| Product | 1-Carbethoxycarbonylmethyl-2-amino-3-carbamoyl-quinoxalinium bromide | HCID 20287983 | — |
Reaction Steps
A solution of 1 g of 2-amino-3-carbamoyl-quinoxaline prepared from 2-chloro-3-carbethoxy-quinoxaline by the method of Gowenlock et al [J. Chem. Soc., 1945, p. 622-5] in 50 ml of dimethoxy ethane and ethyl bromopyruvate was stirred for 2 days and was filtered to obtain 1.44 g of 1-carbethoxycarbonylmethyl-2-amino-3-carbamoyl-quinoxalinium bromide as a yellow crystalline solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04254123 |
| Source dataset | uspto-grants-1981_03 |
| ORD ID | ord-fabeff5d55234d1384552be2114d2314 |
| Source note | uspto-grants-1981_03 |