反应详情

A suspension of 1 g of the product of Step A in 100 ml of ethanol was refluxed with stirring for 90 minutes and the resulting yellow solution was concentrated and cooled. The mixture was filtered to obtain 0.55 g of ethyl 4-carbamoyl-imidazo-[1,2-a]-quinoxaline-2-carboxylate as a pale yellow crystalline solid. Recrystallization from ethanol yielded soft white needles melting at 280°-284° C.

1. temperaturewas refluxed
2. concentrationthe resulting yellow solution was concentrated
3. temperaturecooled
4. filtrationThe mixture was filtered