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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1267762Generated: November 1, 2026

Ethyl 2-(7,7,8,8,8-pentafluorooctyl)-9-decenoate → 11-[(3RS,4RS)-3-ethyl-7-hydroxy-3-(4-hydroxyphenyl)thiochroman-4-yl]-2-(7,7,8,8,8-pentafluorooctyl)undecanoic acid

https://huagongshe.com/reaction/1267762

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 2-(7,7,8,8,8-pentafluorooctyl)-9-decenoateHCID 18546272—
Reactant10-[(3RS,4RS)-3-ethyl-7-hydroxy-3-(4-hydroxyphenyl)thiochroman-4-yl]-2-(7,7,8,8,8-pentafluoro-octyl)decanoic acidHCID 18546277—
Product11-[(3RS,4RS)-3-ethyl-7-hydroxy-3-(4-hydroxyphenyl)thiochroman-4-yl]-2-(7,7,8,8,8-pentafluorooctyl)undecanoic acidHCID 18546267—

Reaction Steps

Starting with the allyl compound prepared in Example 13 and the ethyl 2-(7,7,8,8,8-pentafluorooctyl)-9-decenoate prepared in Example 8, the same procedure as shown in Example 13 was repeated to give 11-[(3RS,4RS)-3-ethyl-7-hydroxy-3-(4-hydroxyphenyl)thiochroman-4-yl]-2-(7,7,8,8,8-pentafluorooctyl)undecanoic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06552068B1
Source datasetuspto-grants-2003_04
ORD IDord-ac7cd815412744e485122b34a7176d4c
Source noteuspto-grants-2003_04