反应详情

A suspension of 2-hydroxy-4-methoxybenzaldehyde (6.10 g), 4-methoxyphenylacetylchloride (11.1 g) and potassium carbonate (20 g) in acetone (400 ml) was heated under reflux for 2 hours. The reaction mixture was evaporated to remove the solvent, followed by addition of water. The resulting precipitates were collected by filtration and dried under reduced pressure to give 7-methoxy-3-(4-methoxyphenyl)-chromen-2-one (10.1 g, Yield 89%).

1. temperaturewas heated
2. temperatureunder reflux for 2 hours
3. customThe reaction mixture was evaporated
4. customto remove the solvent
5. additionfollowed by addition of water
6. customThe resulting precipitates
7. filtrationwere collected by filtration
8. customdried under reduced pressure